H065

Psoralen, 99%

CAS number

66-97-7

Molecular formula

C₁₁H₆O₃

Molecular weight

186.17

mp

169-170 °C

Price and availability

25 mg

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100 mg

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500 mg

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Synomym

Ficusin; 7-H-Furo(3,2-g)(1)benzopyran -7-one;

Product information

A naturally occurring furocoumarin, extracted from Psoralea corylifolia and other plants where it appears to serve a defensive role. After photoactivation with UV radiation, it appears to bind DNA through single and double-stranded cross-linking. Anthelmintics, cross-linking reagent, photosensitising agent. Photochemical reagent for the investigation of nucleic acid structure and function.

Safety

Hazard. Xn (harmful)
Risk Statement. Harmful if swallowed. Irritating to eyes, respiratory system and skin.
Safety Statement. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye protection.

References

Cimino, G.D. et al., Annu. Rev. Biochem. 1985, 54, 1151.
Kornhauser, A., et al., Science 1982, 217, 733-735.
Inman, R.B. et al., J. Mol. Biol. 1987, 193, 377.
Cullinane, C. et al. Cancer Res. 1998, 58, 1400-1404.