H040

Isopimpinelin, 99%

CAS number

482-27-9

Molecular formula

C₁₃H₁₀O₅

Molecular weight

246.22

mp

Price and availability

25 mg

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100 mg

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500 mg

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ynomym

5,8-Dimethoxypsoralen; 4,9-Dimethoxy-7H-furo(3,2-g)(1)benzopyran-7-one

Product information

Naturally occurring Furocoumarin from Ruta graveolens and Heracleum lanatum. Strongly inhibits insulin-stimulated lipogenesis. Induces hepatic GSTs and is potent inhibitor of cytochrome P450 1A1/1B1. Oral administration of isopimpinellin, blocks DNA adducts formation and skin tumor initiation by 7,12-dimehylbenz[a]anthracene in SENCAR mice and in mouse mammary gland.

Safety

References

Kleiner, H.E. et al., Carcinogenesis, 2002, 23, 10, 1667-1675.
Prince, M. et al., Carcinogenesis, 2006, 27, 6, 1204-1013.
Mammen, J.S. et al., Pharmacogenet. Genomics, 2005, 15, 3, 183-188.
Kimura, Y. et al. Planta Med. 1982, 45, 183-187.