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H037

Isoimperatorin, 99%

CAS number

482-45-1

 


 

Molecular formula

C16H14O4

 

Molecular weight

270.28

 

mp

 

 

Price and availability

25 mg

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100 mg

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500 mg

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Synomym

Iso-imperatorin; 7H-Furo(3,2-g)(1)benzopyran-7-one,4-((3-methyl-2-butenyl)oxy)-

Product information

Isoimperatorin is a tumor necrosis factor antagonist isolated from Glehniae root or from Poncirus trifoliate Raf.. Competitive inhibitor of cytochrome P 450 1B1. Potent chemopreventive agents against aflatoxin B1-inducible cyotoxicity in H4IIE cells with a bifunctional effects on glutathione S-transferase and CYP1A.

Safety

 

References

Pokharel, Y.R. et al., Carcinogenesis 2006, 27, 12, 2483-2490.
Mammen, J.S. et al., Pharmacogenet. Genomics 2005, 15, 3, 183-188.