H102

Bergapten, 99%

CAS number

484-20-8

Molecular formula

C₁₂H₈O₄

Molecular weight

216.19

mp

190-193^oC

Price and availability

25 mg

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100 mg

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500 mg

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Synomym

5-Methoxypsoralen; 5-MOP; Heraclin; Majudin; Psoraderm;  4-Methoxyfuro(3,2-g)benzopyrane-7-one;

Product information

Intercalating agent for DNA forming covalent cross-links upon UV-irradiation. Bergapten is used in combination with ultraviolet A (UVA) radiation, in the treatment of psoriasis and vitiligo.

Safety

Hazard. Xi (irritant)
Risk. May cause sensitisation by skin contact.
Safety Statement. Wear suitable protective clothing and gloves.

References

Kavli, G., et al., Contact Dermatitis, 1983, 9, 5, 365-366.
Fujita, H. et al. Chem. Lett. (jpn), 1986, 545.
Boyer, V. et al. Biochem. 1988, 27, 3011.
McNeely, W. et al., Drugs 1998, 56, 667-690.