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H101

Bergamottin, 99%

CAS number

7380-40-7

 

 


 

Molecular formula

C21H22O4

 

Molecular weight

338.41

 

mp

53-54 °C

 

Price and availability

25 mg

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100 mg

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500 mg

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Synomym

5-Geranoxypsoralen; Bergamotine; 7H-Fro(3,2-g)(1)benzopyran-7-one,4-((3,7-dimethyl-2,6-octadienyl)oxy)-,(E)-

Product information

Radiation-sensitizing agent. Constituent of bergamot oil. Potent chemopreventive agents against aflatoxin B1-inducible cyotoxicity in H4IIE cells with a bifunctional effects on glutathione S-transferase and CYP1A. Potent inhibitor and inactivator of cytochrome P450 1A1-mediated monooxygenase in both murine hepatic microsomes and in a reconstituted system using purified human P450 1A1.

Safety

 

References

Cai, Y. et al., Carcinogenesis 1997, 18, 1, 215-222.
Mammen, J.S. et al., Pharmacogenet. Genomics 2005, 15, 3, 183-188.